Antibody

Illustration of Antibody
Illustration: Antibody

Doc permission to ask, how do the antibodies work in our body if we suffer from DM type 1?

1 Answer:

Hello Sri,


Thank you for the question.

Antibodies (immunoglobulins) are proteins formed by the body in response to antigens. Normally, antibodies are produced when the body recognizes the presence of bacteria, viruses, poisons, or other foreign matter in the blood. The main producer of antibodies is one type of white blood cell, namely lymphocytes. After being produced, these antibodies can later be paired with antigens and destroy them so they do not cause any harmful effects to the body.


Type 1 diabetes occurs when the body is unable or totally unable to produce insulin due to a disruption in the pancreas. Not yet known exactly what causes this condition. However, genetic factors that cause errors in the immune system's work in recognizing cells in the pancreas that are useful in producing insulin as a foreign object, so it is worth destroying, many staying digadang as the main trigger. In this case, in connection with your question, the body will produce antibodies to cells in the pancreas that should produce the hormone insulin. As a result, these cells are damaged, and insulin production is disrupted.


There is no direct link between antibodies that are mistakenly formed by the body to destroy pancreatic cells and antibodies formed by the body when recognizing other antigens. However, increased sugar levels in people with type 1 diabetes that are not controlled, can apply antibodies that the body produces when recognizing other antigens. As a result, the work of these antibodies in destroying antigens (foreign bodies that can actually damage tissue in the body) will also be ineffective. Therefore, many uncontrolled type 1 diabetics become more prone to illness due to decreased body endurance.


Does this answer your question? If not, don't hesitate to read a lot of biology books or make new question threads clearer.


I hope this helps.

: by

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