Are Mothers With TGA IVS PDA Potentially Pregnant With Fetal Heart Abnormalities?
Hello doctor, r nDoes the mother who has given birth to a baby with a diagnosis of TGA IVS PDA have the potential for congenital heart abnormalities in subsequent child pregnancies?
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Transposition of the great arteries (TGA) is a condition in which two large arteries coming out of the heart are switched. The two arteries that come out of the heart in normal conditions are the aorta from the left ventricle to the entire body and the pulmonary artery from the right ventricle to the lung. In TGA conditions, the aorta exits the right ventricle and the pulmonary artery exits the left ventricle. As a result, blood from the lungs that should be flowed throughout the body in a state rich in oxygen cannot be flowed throughout the body and instead flowed back to the lungs. And vice versa, blood from the whole body that should go into the lungs to be oxygenated cannot go to the lungs and instead flow back to the whole body, so the child will become tight and blue.
There are three types of TGA, TGA with intact ventricular septum (IVS), TGA with ventricular limiting defect (VSD), and TGA with VSD and narrowing of the pulmonary arteries. In the patient you mentioned, TGA IVS means that the patient has TGA with the condition of the right and left heart chambers fully separated. That is, blood that contains oxygen can not be mixed with blood that does not contain oxygen. In this condition, the patient will show symptoms very quickly, immediately after birth. However, this patient also has a PDA or patent ductus arteriosus. The ductus arteriosus is a channel that connects the aorta to the pulmonary artery. This channel is normal in the unborn child and will close after the baby is born. If this channel persists, it is called a PDA. Luckily for this patient, the PDA provides oxygen to be circulated throughout the body, so that there is enough time for surgery to deal with the TGA that occurs.
TGA is caused by a disruption during the process of heart development in the womb. The cause of this disorder is unknown. TGA is rarely associated with genetic problems, so mothers who have given birth to babies with TGA do not have a higher risk for subsequent pregnancies. Some studies say, TGA is associated with rubella or other virus infections during pregnancy. Maternal age over 40 years, alcohol consumption, and diabetes are also associated with the occurrence of TGA. Therefore, to prevent recurrence, mothers should be given a vaccine to prevent rubella infection. Mothers should also avoid alcohol consumption. If the mother has diabetes, she must maintain blood sugar levels and tight control during pregnancy.
That's all information from me. I hope this helps.