Can Progesterone And HCG Be Examined Simultaneously?

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Good afternoon, I want to ask. Are progesterone tests often performed to diagnose miscarriage? When do you think the HCG and progesterone tests are done together? Thank you, please answer

1 Answer:

Hello. Thank you for the question submitted to HealthReplies.com. We can understand the concern you feel.


Progesterone is a hormone that has many functions, one of which is to regulate the menstrual cycle and prepare the female body for pregnancy. This hormone also serves to prepare the breasts so they can breastfeed later after becoming pregnant. Examination of the hormone progesterone uses blood samples and is usually intended to examine the process of ovulation (release of eggs from the ovaries), fertility problems, and menstrual disorders.


Based on recommendations from the Royal College of Obstetricians and Gynecologists (RCOG), examination of the hormone progesterone level is not a routine examination performed in cases of miscarriage. In general, special examinations are not always done on couples who experience one or two miscarriages due to miscarriages that occur 1-2 times usually occur by chance alone (not due to chronic illness), for example due to trauma. Certain investigations are usually offered to couples who miscarry with the following characteristics:

Having recurrent miscarriages, which is 3 times or more miscarriages in a row
Having miscarried twice in the late 30s or around 40 years, or pregnancy has been waiting for so long
Miscarriages occur in the second trimester of pregnancy (gestational age above 14 weeks)

Until now, there are several known causes of recurrent miscarriages, including:

Antiphospholipid syndrome, which is a blood clotting disorder in which the body's own immune system produces abnormal antibodies that actually attack the fat component (phospholipids) in the blood so that the blood becomes more sticky and tends to clot; this condition causes interference with the process of attachment to the fetus in the uterine wall and interferes with blood flow to the placenta and fetus
Other inherited blood clotting disorders, for example factor V Leiden, S protein deficiency
Chromosome abnormalities, usually more common in older couples
Weakness of the cervix (incompetent cervix), causes cervical dilation too early so that a miscarriage occurs

In addition to the known causes of recurrent miscarriage, there are also other causes that may cause recurrent miscarriages, but valid scientific evidence is not enough to be the basis that the following are definite causes of miscarriage. Some of the possible causes of recurrent miscarriage include: abnormal uterine shape, polycystic ovary syndrome, infection, diabetes, thyroid disorders, etc.


Therefore, the supportive examination recommendations given by RCOG include examinations aimed at identifying the causes of recurrent miscarriages that have been mentioned. Examples of suggested investigations include: blood, chromosome examination, pelvic ultrasound (USG), hysteroscopy, and laparoscopy. Determination of which investigations are needed for each case is based on clinical findings on the history and physical examination by the doctor.


We recommend that you consult directly with the obstetrician and gynecologist who treats you so that your condition can be evaluated and treated appropriately. To enrich insight, you can read articles about supporting examinations of recurrent miscarriages. Thus information from us. Hopefully always healthy. May be useful.

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