Can Several Types Of Drugs For ARV Therapy Be Taken At The Same Time?

Good evening … r n r nI am. People living with HIV / AIDS are new and have started the 2-week ARV therapy. R nThe medicine that doctors give Lamivudin and Neviral with a dose of 1 tablet each in the morning and evening … so a total of 4 tablets a day that I have to take r n r n Can I have 4 tablets at one time, for example at night? r n r nThank you

1 Answer:

Good evening, thanks for asking at HealthReplies.com. Taking drugs is sometimes an easy part of treatment because all we need to do is consume as directed. However, it cannot be denied that there are still many questions regarding this matter and it is not uncommon for a treatment to not run optimally or even fail because of a misunderstanding between the doctor and the patient, so expressing your confusion with this question is a very good decision.


The two drugs that you mentioned are drugs that are commonly given as treatment to PLWHA, and consist of lamivudine and nevirapine. These two drugs do not interact with each other and thus should be taken together.


Regarding your question, this is where you need to understand that dividing the drug into several doses in a day, such as 1x a day, 2x a day, 3x a day and so on is done because the levels of drug content in the blood vary. For example, some medicines have levels in the blood that start to fade after 8 hours, so to ensure that the levels remain stable in the body, every 8 hours the patient must take the drug again. And because there are 24 hours a day, be advised to take the drug 3 times a day.


The same is the case with drugs that are taken 2x a day, which means that the drug will start to fade in the body after 12 hours and the patient has to take the drug again to raise his levels again.


If you make one medicine that is supposed to be consumed in the morning and at night and consumed only at night, what happens is that in the evening, the drug content in the body will be so high that it may have side effects, and after about 12 hours, or during the afternoon to the evening, the drug levels in the body will be very low or may not even be available to work. So that the treatment you are undergoing is not optimal.


So the conclusion comes back again, obey the rules of use that have been given by your doctor and take your medicine in this way, which will be better if it is at the same time with the same breaks every day. If you find it difficult to follow the rules of 2x a day, tell your doctor and maybe you will find a drug that has a higher content so that it can last even though it is consumed once a day. So, hopefully it answers your question.


dr. Amadeo D. Basfiansa

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