Can You Take Ketoconazole Together With Antibiotics?

Illustration of Can You Take Ketoconazole Together With Antibiotics?
Illustration: Can You Take Ketoconazole Together With Antibiotics?

Hi, I want to ask. R nIs it safe to take ketoconazole together with sisoprim and dexteem plus?

1 Answer:

Hello Desyyy, thank you for asking

Ketoconazole is a drug used to treat skin infections caused by fungi. There are several preparations including oral / drink in the form of tablets, ointments to be applied and shampoo to be used when washing hair. Need to be careful in using ketoconazole in women planning a pregnancy, pregnant women and babies, must be under the supervision of a doctor for its use.

In its working system in the body, sometimes ketoconazole can interact with other drugs, the results can make ketoconazole work obstructed, or it can also have a too strong effect if used together, some drugs that interact with ketoconazole include:

gastric drugs such as antacids, sucralfate, and the like which inhibit the production of excess stomach acid. When taken with ketoconazole, the action of ketoconazole can be hampered by this gastric drug.
birth control pills, the effect of birth control pills to prevent pregnancy will decrease due to the effect of ketoconazole.
Lovastatin, simvastatin, can cause muscle cramps when taken with ketoconazole
Rifampicin, decreases the effect of ketoconazole

Sisoprim is a drug containing the sulfametoxazole class of antibiotics which can be used to treat diseases such as ear infections, respiratory infections, and urinary tract infections, all of which are caused by bacteria. Antibiotics for the sulphametoxazole class will only react if taken together with certain drugs, namely:

warfarin, increases the risk of bleeding effects
antidiabetic drugs such as glimepirid, the side effects of glimepirid will be easier if taken together with ketoconazole
clozapine and pyrimethamin have a high risk of developing blood cell disorders when taken with ketoconazole

Meanwhile, dexteem plus is an anti-inflammatory and anti-allergic drug that is packaged in one tablet dosage. Both of these drug combinations work by suppressing the immune system in the body and inhibiting allergic reactions and inflammation. So that its use is very useful in inflammatory and allergic disorders that attack the respiratory tract, eyes and skin.

Some drugs that react and harm the body when taken together with anti-inflammatory and anti-allergic drugs include rifampicin, phenobarbital, ephedrine, phenytoin and some drugs that have urinary effects such as diarrhea drugs.

Of the medicinal preparations that you conveyed, of the three are still safe to consume together, it's just that it needs to be considered in consuming these drugs, including:

Always take drugs under the supervision of a doctor, especially drugs if they are used for a long time. In order to avoid unwanted side effects, either side effects that appear quickly, or in the long term.
Always take medicine by using water, so that the drug's function is not hampered by the content in drinks other than water, such as coffee, tea, or milk.
Take the medicine according to the doctor's recommendation, both how to take it (before or after eating), the length of time to take the drug and the time it takes to take the first drug and the next, try to take the medicine on time, so that you can get the benefits of the drug optimally.

If you still want to know the effect of these three drugs on your body, then you can return to control and ask the doctor who prescribed the drug. Because the doctor knows better about the real situation of your body, so it must have been properly considered according to the therapeutic goals and possible side effects.

A few of us, hopefully useful. Thank you

dr. Ciptanti

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