Causes Of Increased CK Into The Blood In Patients With Tetanus?
Good night. I want to ask about the relationship between increased serum creatinine kinase and muscle rigidity in tetanus cases. Can you give examples and mechanisms of action like that? thank you
Good afternoon, thank you for asking again.
Creatinine kinase or commonly abbreviated as CK is an enzyme found in cytosols and mitochondria in tissues that require high energy, and the most composition of these enzymes can be found in muscle tissue. Serum CK is the level of CK enzymes found in the blood, the levels can be used as a marker of muscle tissue damage. In the case of tetanus, muscle rigidity occurs continuously resulting in damage to muscle tissue that causes leakage of CK enzymes into the blood and causes an increase in serum CK.
Examples of other cases that can cause an increase are, for example, rhabdomyolysis and heart attacks (myocardial infarction), where there is damage to muscle tissue resulting in leakage of the CK enzyme into the blood.
I hope this helps.