Complete Blood Count Results For Down Syndrome Sufferers?
a 12 year old boy with complaints of instantaneous weakness and worsening. born with a diagnosis of Down syndrome and mental retardation. The doctor’s examination showed that the patient had physical abnormalities associated with Down syndrome, pale mucous membranes, and mild splenomegaly. there was no visible lymphadenopathy or hepatomegaly. the doctor recommends a complete blood count and urinalysis. The result is that erythrocytes and hemoglobin decrease dramatically. The total leukocyte count was 225×10 to the power of 9 / L. In the blood smear: 82% blast cells, 2% promyelocytes, 2% myelocytes, 1% metamielocytes, 7% segment neutrophils and 6% lymphocytes. Platelets decrease, aeru blast is found inside the blast cell. Urinalysis is normal. The results of cytochemical staining showed positive results for sudan black B and NASDCA estrene without inhibition by sodium. What is the most likely diagnosis for this case?
Hello Fanny, Thank you for your question on HealthReplies.com
Down syndrome or Down syndrome is a genetic disorder caused by a chromosome 21 disorder that results in intellectual and developmental delays, and is characterized by a flat or flat nose, low ears, a short neck, a large tongue, and narrow eyes. Many health problems experienced by children with Down syndrome, such as heart problems, eye disorders such as cataracts from birth, hearing problems caused by anatomical conditions of the ear, frequent infections because children with Down syndrome will have their immune system attacked, decreased thyroid hormone (hypothyroidism) , and blood disorders.
Some of the possible blood disorders based on the clinical and blood test results above are:
Leukemia, or blood cancer, is a blood disorder most often experienced by children with Down syndrome Anemia, or a deficiency of red blood cells. Polycythemia vera or increased levels of red blood cells.
Thank you, hope it is useful. Dr. Nurmarwiyah