Does The Difference In Blood Rhesus Make It Difficult To Get Pregnant?

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I want to ask, my blood type is B rhesus positive, while my husband’s blood type O rhesus negative. Can this difference in rhesus make it difficult for me to get pregnant? and if I get pregnant is there any negative impact on the fetus?

1 Answer:

Hello Atiks,

Rhesus is a special protein on the surface of red blood cells. People who have this protein are rhesus positive (Rh +), while those who don't have this protein are called rhesus negative (Rh-). The difference between husband and wife rhesus does not affect the pregnancy program. You can still get pregnant as long as the conditions of the reproductive organs, hormones, egg cells and sperm cells are all good.

However, the difference in rhesus between mother and fetus can cause problems that endanger the fetus in the form of erythroblastosis fetalis, in which the fetal red blood cells are attacked by antibodies from the mother's body. This condition will get worse in the second pregnancy and later.

The following is what might happen in the relationship between husband and wife rhesus:

Rh + husband and Rh + wife: the fetus must be Rh + and there is no problem Rh husband- and Rh- wife: the fetus must be Rh- and there are no problems Rh + husband and Rh + wife: the fetus can be Rh + can be Rh- and there may be problems if the fetus turns out to be Rh +. If the fetus and mother are both Rh- then there is no problem Rh husband- and Rh + wife: the fetus can be Rh + can be Rh- but it does not cause problems -> this point is what happens in your case. while the fetus is rhesus positive, this will trigger the mother's body to produce antibodies that harm the fetus. Maternal blood cannot mix with fetal blood. Usually the first pregnancy does not cause serious problems, but the problems will start to appear and become more severe in later pregnancies.

Meanwhile, if the mother is rhesus positive and the fetus is rhesus negative, then there is no problem to worry about. If you are still worried, I suggest that you consult further with your obstetrician about the differences in rhesus between you and your husband so that you can get a more detailed explanation.

The following articles are related to the topic of your question:

Rhesus condition of pregnant women with fetal safety

Thank you and hope it helps,

dr. Devika Y

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