Effect Of The Active Substance Of Cannabis On HIV / AIDS?
alodok I want to ask r n after I read the article about the THC (tetrahydrocannabinol) content in cannabies can fight the Hiv virus? because it can improve the immune system? and participate in suppressing the HIV virus? is it true? r nif so why not conduct research for HIV drugs from these substances? r nthank you
Hello adnun, thank you for the question.
Tetrahydrocannabinol is indeed one of the active substances in cannabis or marijuana. Actually, this active substance and marijuana have been known to have several health benefits. However, its use must be in accordance with a doctor's prescription, because if it is used only for pleasure, this will actually have a bad impact on the body and cause dependence.
Research with marijuana has actually been carried out a lot, but it is necessary to know that research in the medical field, especially for treatment or therapy, does have many stages of research, especially when the results of this study will be used by humans, it is necessary to repeat clinical trials and follow up the results within a period of time. long to really ensure the minimum possible side effects and with the maximum possible benefit that can be caused by the drug. Because patient safety is the most important thing. The steps that need to be taken until the drug can be marketed must go through several stages:
1. First, the discovery and development of new drugs. It is necessary to identify chemical compounds that are "believed" to have a certain effect on the body, these compounds are then narrowed down to find the main compounds that have the most influence, and various tests are carried out regarding their safety levels, side effects, how long they will last and circulate in the body. etc.
2. Second, the pre-clinical test. Here, a more detailed investigation is carried out on the main compound, to find out by conducting tests on living cells, bacteria, tissue culture and on animals.
3. Third, clinical trials. Here, research is conducted on humans. Before starting clinical trials in humans, careful planning will be made about what to do and the consideration of the ethics commission regarding this stage of research. Clinical trials in humans themselves have several stages, around 3 stages, starting with a small sample and then getting bigger. This test is primarily to test the level of safety of the drug in humans.
4. Fourth, FDA approval or other authorities.
5. Fifth, monitoring drugs on the market. So even when a drug has been marketed, post-marketing monitoring will still be carried out to determine the effect of the drug in the wider population and if it is known to have a harmful effect this drug will be withdrawn from the market.
So there are many steps that need to be done before marketing a new drug. the time it takes to research one type of drug can take dozens to decades before it can be marketed.
Regarding the effect of the active substance of cannabis on HIV / AIDS, some studies have stated that it can reduce complaints such as nausea, numbness, pain, etc. However, there are studies that state that the effect of marijuana use on HIV virus suppression is not statistically significant. However, further research is certainly needed to determine the effect of this active substance and if it is proven that it can be one of the therapeutic options in patients with HIV / AIDS, it certainly does not rule out the possibility that new drugs from this active substance will be developed.
Hope this information is useful, thank you.