Excess Folic Acid Can Cause Autism?

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Illustration: Excess Folic Acid Can Cause Autism? todaysdietitian.com

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1 Answer:

Hello. Thank you for the question submitted to HealthReplies.com. We can understand the concern you feel.


In general, pregnant milk is not a requirement for pregnant women to drink if your daily nutritional intake is sufficient and in accordance with the concept of balanced nutrition. Pregnant women need to eat a nutritionally complete and balanced diet, which consists of carbohydrates, proteins, fats, minerals, vitamins, and fiber. The World Health Organization (WHO) recommends an additional energy of 180 kcal / day for pregnant women in the 1st trimester, and 300 kcal / day in the 2nd and 3rd trimesters. These additional calories are beneficial for the needs of pregnant women and fetuses, and can be met from any source, both milk and other foods. Additional micronutrient substances needed by pregnant women include:

Iron, useful for the formation of red blood cells, contained in: liver, red meat, green vegetables, fish
Folic acid, useful to support the growth and development of the fetal nervous system, contained in: green vegetables, cereals, oranges, grapes; it is recommended that pregnant women receive 400 ug / day supplementation from 3 months before pregnancy (if without a history of giving birth to a baby with a neural tube defect) or 4 mg / day (if you have a history of giving birth to a baby with a neural tube disorder)
Vitamin C, functions as an antioxidant, contained in oranges, apples, and other fruits
Mineral substances to support fetal brain development, including iodine (contained in iodized salt), iron, zinc (contained in meat, seafood, nuts, dairy products), and copper (contained in liver, seafood, nuts- nuts)

Have you ever had a history of giving birth to a baby with a neural tube disorder before? Folic acid is one of the nutrients contained in the Lactafar brand supplement you mentioned, with a level of 800 ug per capsule. This figure is sufficient for the needs of pregnant women in general who have no history of giving birth to babies with neural tube abnormalities. If the doctor advises you to get more folic acid, the doctor may find certain indications that make him recommend that you consume more sources of folic acid. As explained earlier, it is recommended to increase the intake of folic acid to 4 mg / day in pregnant women who have risk factors for folic acid deficiency.


Literature review by Wiens et al. published in 2017 shows that various studies on the effect of folic acid over supplementation on the incidence of autism spectrum disorders still show conflicting results. In addition, there are no studies in humans that prove a causal relationship between folic acid supplementation and autism spectrum disorders. Therefore, further studies are still needed to find out for sure the causal relationship between the two things.


Feel free to consult with your obstetrician and gynecologist who treats you to get an evaluation of your nutritional needs and the fetus as well as planning your required nutritional intake. To enrich insight, you can read articles about healthy food for pregnant women. Thus information from us. Hopefully always healthy. May be useful.

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