Explanation Of Syphilis Lab Results?
Tonight, I just found out that I had syphilis when I was a blood donor. And yesterday I went straight to Prodia to check blood. Now based on the results of the VDRL / RPR lab it is reactive 1: 4 Then the TPHA is reactive 1: 1280. So my question is, what phase of syphilis have I suffered? Primary, secondary, latent or tertiary?
Good morning, thanks for the question
Syphilis is a chronic infectious disease caused by Treponema pallidum which is chronic and can attack organ systems systemically including the heart and innervation. If left untreated, syphilis can progress to the next phase and extend to other parts of the body outside the genitals. Symptoms of syphilis based on disease stages are divided into primary, secondary, latent and tertiary syphilis.
One of these serological tests is to determine the activity of the disease, the stage of the disease and determine the appropriate treatment.
The TPHA test is specific to treponema. The results of this test will show positive / reactive results for life even though the treatment response is quite good. However TPHA tests cannot be used to distinguish between active infections and those that have been treated adequately. The results of your examination mean that there is a positive infection with a specific treponema that causes syphilis.
Whereas VDRL or RPR tests are non-specific but are able to detect acute infections and active reinfection, and monitor the success of therapy. If the results of this examination are 1: 4 or 1: 8, they are classified as late latent infection, then need to be treated as late latent syphilis and evaluated 3 months later to assess treatment response. If after the evaluation, the results of the RPR titre are down, the treatment is considered successful, so the evaluation will be carried out over a longer period.
Consult again with a specialist skin genitalia for treatment plans and future disease evaluation plans.
That's all, hope you can help.