How To Determine Cow’s Milk Allergy From IgE Examination?

My child was diagnosed by a doctor who is allergic to cow’s milk. But as we did a blood test and totally we finally found that our child’s hb was low, after the blood transfusion our child became restless, slept soundly. Our position is already using neocate milk. Results from total ige levels 10.23 r nYg We would like to ask whether from the results of total ige levels that our child is allergic to cow’s milk?

1 Answer:

Good evening, thanks for the question


Cow's milk allergy is an undesirable reaction mediated through an immune response to cow's milk protein.


Cow milk allergies can be divided into:


1. IgE mediated, namely cow's milk allergy mediated by IgE. Symptoms occur within 30 minutes to 1 hour after consuming cow's milk protein. Symptoms that appear in the form of skin rashes, vomiting, diarrhea, vomiting, spasms, to anaphylaxis.


2. Non-IgE mediated, namely cow's milk allergy that is not mediated by IgE, but mediated by IgG. Clinical symptoms occur more slowly (> 1 hour) after consuming cow's milk protein. Symptoms that appear like diarrhea, colic pain, or failure to grow.


There are no typical symptoms for cow's milk allergy. Symptoms due to cow's milk allergy include disorders of the digestive tract, skin and respiratory system.


The diagnosis for an IgE-mediated type of cow's milk allergy is by symptoms and a specific IgE test (skin prick test or specific RAST / IgE test) is performed.


If the results are positive then elimination of foods containing cow's milk protein. If the results are negative, then foods that contain cow's milk protein can be given back.


Serum levels of specific IgE antibodies for cow's milk are positive if> 5 kIU / L in children aged ≤ 2 years and> 15 kIU / L in children aged> 2 years. This examination has a high enough confidence rate according to research.


If your child is under 2 years old then it is concluded that the IgE value is positive, coupled with the current condition, doctors have given amino acid formula (neocate) milk which is non-allergenic milk as one of the choices of formula milk in babies with cow's milk allergy.


Non-allergenic milk is given until the baby is 9 or 12 months old, or for at least 6 months. After that period, a re-examination is carried out, if symptoms do not occur, it means that the child is tolerant and cow milk can be tried to be given back. If symptoms recur then continue again for 6 months and so on.


So, hopefully you can answer


Wassalam, Dr. Farah

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