How To Use Corticosteroids In Patients With Guillain Barre Syndrome?

Illustration of How To Use Corticosteroids In Patients With Guillain Barre Syndrome?
Illustration: How To Use Corticosteroids In Patients With Guillain Barre Syndrome? Bing

, I once read a journal that said that corticosteroids are not effective in the treatment of GBS. but until now it is still used as a supportive therapy in GBS. what is the reason corticosteroids are still used? please answer. thanks

1 Answer:

Hello sister Ivana, it is true that many studies have been carried out and many of them have concluded that there is no significant difference in symptom improvement during the use of corticosteroids in GBS patients and compared to only Plasmapharesis or Intravenous Immunoglobulin (ivIG) treatment. Examples of the following clicks: administration of corticosteroids and IvIg results in improvement of symptoms of weakness in about 28 days, and patients only with IvIg of 51-55 days of improvement, but there are things to note regarding the side effects of corticosteroids such as increased blood sugar and blood pressure, especially in patients who have a history of diabetes and hypertension, may even have to be careful in patients who have a history of gastric bleeding should not be used in such patients.


Supportive therapy with corticosteroids used to be aimed at helping treatment such as preventing an autoimmune process from forming, because the concept of GBS is an autoimmune disorder so that administration is expected to suppress the body's immune process producing the wrong immune attack to nerve cells. The main treatment is plasmaparesis and IvIg which aims to eliminate and clean immune cells that are being misrecognized attacking the body.


In some remote areas, the use of corticosteroids is still used because there is no availability of plasmapharesis and IvIg facilities or the referral process is difficult while the patient is already in a fairly severe condition. However, it is recommended to treat GBS wherever possible with plasmapharesis or IvIg, which is quite one of the uses. Hope it is useful.


Click journal: the use of a type of corticosteroid that might help recovery.


Click the article: GBS and its handling

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