IGRA Test On A History Of TB Patients Who Have Been Cured?
Good morning doctor … I want to ask .. last year I suffered from TB glandular .. a lump in the neck and armpit .. then I treated 9 months and in November 2019 I was sentenced to recover with the doctor. What I want to ask is about the IGRA + medical check-up test that I will do for job selection. Will someone who has recovered from glandular TB be able to pass the IGRA test? thanks. Explanation please.
Hello Putra, Thank you for the question.
Interferon-gamma release assay (IGRA) examination is a blood test that is used to detect tuberculosis (TB) infection in the body. This examination aims to detect the presence of immunity produced in response to infection with the bacterium Mycobacterium tuberculosis as a cause of TB. Thus, anyone who has been infected with this bacterium will have positive results. You need to know that people who are infected with this bacteria will not necessarily experience symptoms of TB. In such cases, the sufferer is said to have latent TB infection. However, if the patient experiences symptoms then the case is said to be an active TB infection. IGRA examination cannot distinguish latent TB infection from active TB infection.
If in the past you have been declared cured, there is still a possibility that you can be infected again but not cause symptoms (latent TB infection) so that the results of the IGRA examination can be positive. This does not only apply to you (who have already had TB) but also to others who have never had TB. Anyone who has been infected with this bacterium can have positive test results. Therefore, a positive IGRA examination results usually need to be followed by other examinations such as sputum examination, x-rays, or Mantoux tests, especially if the person has symptoms. In conclusion, this test may be able to give positive results not because in the past have been exposed to TB, but living in TB endemic areas (Indonesia) can cause us to be exposed to these germs at any time; so the results of this examination must be interpreted carefully by the doctor. Always consult the results of your examination with a doctor, yes.
Hopefully this information helps you.