Increased Levels Of Bilirubin In Infants?

Illustration of Increased Levels Of Bilirubin In Infants?
Illustration: Increased Levels Of Bilirubin In Infants? abclawcenters.com

Ass … r nDok want to ask my child for 5 days in the blue light, but there has been no change, in fact the bilirubin levels are getting higher every day, starting on the first day 13,17,21,22 and last 23, please explain ,, , r nAnd I hope my child can come home as soon as possible …

1 Answer:

Hello Rezza,

Bilirubin is a yellowish red substance that comes from the breakdown of hemoglobin found in red blood cells. Neonatal hyperbilirubinemia is a state of increased levels of bilirubin in the blood that occurs in infants aged 0-28 days (neonates). The cause of hyperbilirubinemia in neonates can be caused by physiological (normal) or pathological (abnormal) conditions. Increased levels of bilirubin can be caused by the breakdown of fetal red blood cells (fetal time) that are still circulating in the baby's body, which has a shorter life span and due to immature liver function.

The pathological state of hyperbilirubinemia is characterized by:

Appears before the age of the baby 24 hours Increases rapidly, bilirubin levels rise> 5 mg / dL / 24 hours or direct bilirubin levels> 20% total bilirubin Accompanied by symptoms of fever, the baby looks weak, does not want to drink, weight loss, shortness of breath, temperature body unstable State of hyperbilirubinemia in low birth weight infants State of hyperbilirubinemia in preterm infants to the soles of the feet and hands (severe hyperbilirubinemia) Persistent hyperbilirubinemia> 2 weeks Causes of pathological hyperbilirubinemia include: bacterial infection, intrauterine / intrauterine infection (congenital syphilis, TORCH ), liver disorders (biliary atresia, hepatitis), hemolytic disorders (abnormal blood breakdown), mothers with diabetes mellitus, congenital hypothyroidism, head trauma during childbirth, etc. There are also hyperbilirubinemia conditions that are influenced by breast milk, namely breastfeeding jaundice (due to lack of breast milk intake) and breast-milk jaundice (a result of the components of the milk itself).

Diagnosis of neonatal hyperblirubinemia based on history (when the appearance of jaundice, breast milk intake, history of pregnancy and childbirth, etc.), physical examination, and supporting examinations such as blood laboratories (total, direct, indirect, peripheral blood smear, blood type, Coombs test, complete blood count, CT-scan, etc.

To reduce bilirubin levels in neonates, light therapy or exchange transfusion can be used. Light therapy will convert the bilirubin in the body into a water-soluble form, so that it can be excreted with urine. An exchange transfusion involves "exchanging" the baby's blood with blood from a normal donor. Indications for each therapy depend on the level of bilirubin, the age of the baby, and whether the baby is born enough or less months. For example, a 3-day-old infant with bilirubin> 18 mg / dL is an indication for light therapy, if the bilirubin> 30 mg / dL means that the baby has an indication for exchange transfusion. In addition, it is also necessary to find out where the hyperbilirubin originates in infants and treat it, for example giving antibiotics if the cause is infection or surgery if the cause is biliary atresia. The most worrying complication of hyperbilirubinemia is kernicterus, where excess bilirubin accumulates in the brain tissue, causing seizures and death.

To determine the cause and appropriate treatment, direct examination by the pediatrician in charge is necessary. Please consult further with the doctor who treats your child.

Thus the explanation from me, may be useful.

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