Testosterone In Babies Is High?
Good afternoon HealthReplies.com, I have a child born at 1975 grams at 36 weeks of age, with penoscrotal hypospadias disorder, the testosterone level is 2.78 ng / ml. Is the testosterone level within the normal range? Do you need therapy? Thank you
Hello, good afternoon Avicenna.
Normal testosterone levels will vary according to the reference value used as a reference from each laboratory. Based on the international reference value by the University of Iowa, the normal testosterone level in newborn boys who are term (36 weeks gestation - 4o weeks) is 75-400 ng / dL, which when converted into units of ng / mL to 0.75-4 ng / mL. Meanwhile, based on international reference values from the British Medical Journal, normal testosterone levels in male infants aged less than 10 days are 2.5 - 11.1 nmol / L, which when converted into units of ng / mL is around 0.72 - 3.20 ng / mL. Thus, your child's testosterone level based on this reference value falls within the normal range.
Regarding hypospadias, is a congenital disorder (congenital) in the form of a defect in the position of the urinary hole (urethral meatus) which is not in its normal position (not at the tip of the penis). Penoscrotal hypospadias means that the urethral meatus is posterior (below), that is, between the base of the penis and the scrotum. This disorder is caused by disruption in growth and development of the genitals while the fetus is in the womb, where the cause of this condition is not certain. However, hypospadias is thought to be caused by the inhibition of the work of the hormone testosterone (male sex hormone). In addition, other factors that are also thought to have an impact on hypospadias include heredity, maternal age over 40 when pregnant, and exposure to chemical compounds (especially pesticides) or cigarette smoke during pregnancy.
The need for therapy can only be concluded by the doctor who examined your child directly, because the need for treatment is determined by the severity of the hypospadias experienced. The goals of treating hypospadias are to get urine to flow out through the front end of the penis, keep the penis from bending when erect, and make the penis look as normal as possible. In general, if the urethral opening / urethral meatus is far from the location it should be, then surgery to remove the urethral opening is necessary. This operation is ideally performed when the child is four months to 1.5 years old. If not treated properly, patients who experience hypospadias can experience several complications, namely: difficulty learning to urinate in the toilet, as an adult there can be disturbances due to abnormal ejaculation, and psychological problems due to insecurity.
We highly recommend that you check and reconsult your child to a pediatric surgeon to get a conclusion on the best treatment that can be done and a follow-up plan for the future.
I hope this helps.
Greetings, dr. Denisa