The Effect Of Epilepsy Drugs On A Woman’s Menstrual Cycle?
Hello. My ode from a year ago. Since this epilepsy, my menstrual cycle is not regular. And now it’s 6 months without menstruation. What I want to ask is whether OAE affects a woman’s menstrual cycle? thank you
Hello Almashyra, thank you for the question for HealthReplies.com
Epilepsy in women can be different from epilepsy in men. The main hormones found in women, namely estrogen and progesterone, have an effect on the excitation of neuron cells in the brain. Estrogen is a hormone that excites neuron cells, while progesterone is a hormone that relaxes neuron cells. Because of this hormonal mechanism, some women with epilepsy may have a tendency to have more seizures around the time of ovulation (when the hormone estrogen is high), or just before menstruation when the hormone progesterone is very low.
Apart from the hormonal influence on epileptic seizures, epilepsy itself is known to affect a woman's hormonal condition. Women with epilepsy are more likely to experience reproductive hormone-related disorders including PCOS, hyperandrogenemia (excess androgen hormones), infertility, hypothalamic amenorrhea, hyperprolactinemia, all of which can affect the menstrual cycle and prevent women from experiencing menstrual cycles (amenorrhoea). The use of antiepileptic drugs is also known to affect the menstrual cycle and cause a woman with epilepsy to experience amenorrhoea. The antiepileptic drugs that have this effect are mainly Carbamazepine and Phenytoin, however Valproic acid is also known to cause hormonal disturbances and amenorrhoea.
If you experience a disruption in your menstrual cycle, it's a good idea to discuss this directly with the neurologist who treats you and your neurologist will refer you to an obstetrician if necessary.
So much information from me, hopefully it will be enough to answer