Toxoplasma Test Results?
I am 1 month pregnant, the doctor suggested for a blood test. The results are anti-toxo IgG 6474.00 reactive and 1.30 reactive IgM. Anti CMV IgG reactive 30.78 and anti CMV IgM 0.23 nonreactive. Can I still continue the pregnancy?
Good evening, thanks for the question
Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii. Symptoms of toxoplasmosis in adults are usually not typical or may be symptomatic but are very mild. Pregnant women who are infected with toxoplasmosis, both asymptomatic and mild symptoms can transmit the disease to the fetus they are carrying.
Acute toxoplasmosis in untreated pregnant women can cause congenital toxoplasmosis in the form of severe disability, such as mental retardation, neurologic abnormalities, blindness and epilepsy. Post-birth may be symptoms of abnormalities in infants not yet seen, but will be seen as the baby grows and develops.
Serological examination in pregnant women followed by ultrasound examination to determine abnormalities in the fetus they contain are needed to strengthen the occurrence of toxoplasmosis infection in the mother.
Positive IgG titers indicate that Toxoplasma infections have occurred both recently and in the past. Positive IgG with negative IgM indicates that infection had occurred more than one year ago.
In acute infections, both IgG and IgM will increase within 1-2 weeks after infection. IgM antibodies can still be detected for several months or even years after the acute phase. In addition, in some people, IgM antibodies can be a false-positive reaction, so it is necessary to do a re-examination to confirm that acute toxoplasma infection is really happening.
In the case of mothers where positive IgM and IgG results indicate new infection that occurs less than 12 months, or a false-positive IgM reaction. To confirm it, a re-examination is required according to the doctor's recommendation. These conditions need treatment and evaluation, both for mother and baby. If acute infection is suspected, a repeat test should be done within 2-3 weeks, and consider giving the antibiotic spiramycin immediately, without waiting for the results of the retest.
In women suspected of having acute toxoplasma infection in the first trimester or early second trimester, spiramycin is given until delivery.
Similarly, cytomegalovirus titers, the possibility of the virus infection has occurred in more than 3-4 years ago, meaning that there is no acute infection. But still needed an evaluation by a doctor.
The doctor will also make observations of the condition of the fetus by ultrasound examination to monitor the growth of the baby in the womb. Consult with your obstetrician because in cases like this a more comprehensive handler is needed for both mother and baby.
That's all, hope you can help
Wassalam, Dr. Farah