Treatment For HIV Sufferers.?
I want to ask, why do people with HIV stage IV with toxoplasma cerebri and CMV retinitis not be given ARV first and fix Toxoplasma and CMV first? Then why when at the beginning has been given cotrimoxazole and finally replaced with clindamycin? Thank you
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Toxoplasmosis is a sporozoa toxoplasma gondii infection in the human body. These sporozoa are transmitted from animals to humans, which is the result of consuming meat that is not cooked and containing toxoplasma or consuming vegetables containing toxoplasma that is not washed clean or in contact with contaminated cat feces.
Toxoplasma which infects healthy humans, generally does not cause symptoms or appear with mild symptoms. However, infecting people with HIV can cause Cerebri toxoplasmosis. Namely Toxoplasma which attacks the central nervous system of the brain. Allegedly, this infection originated from latent toxoplasma in the body before being infected with HIV. As a result of a decrease in the immune system, causing toxoplasma to become active, it can even reach the brain.
The treatment is given sulfamethoxazole and trimethoprim (incorporated in a drug called cotrimoxazole) by injection into a vein in severe cases (unable to take oral medication). If the clinical condition has improved, the drug can be replaced with pyrimethamine and sulfadiazine if there are no contraindications, by adding folic acid. For some reason, sulfadiazine can be replaced with clindamycin. As for antiretroviral treatment, corticosteroids and other treatments are very dependent on the patient's clinical, CD4 cell count results and viral load. You can discuss with a doctor who handles further yes.
Thus hopefully useful.