Use Of D-dimer Blood Test?
At noon, my wife was given a blood test in dimer. How important is the test and how dangerous if the test result is more than 300, please answer. Tq
Hello Andre Sinaga,
D-dimer is the result of the breakdown of fibrin in blood clots from fibrinolysis. Fibrin is useful for the formation of blood clots (thrombus) when wounds occur in body tissues. D-dimer level examination of the body is useful to determine the state of thrombosis or other conditions such as disseminated intravascular coagulation (DIC). Some other diseases related to thrombosis such as deep vein thrombosis, pulmonary embolism. D-dimer examination is done if the history and physical examination have a tendency to experience the disease.
Increased levels of d-dimer in pregnant women is normal. This results in higher normal reference values for d-dimers in pregnant women. The normal level of d-dimer in adults (not pregnant) is <500 ng / ml. In pregnant women trimester 1 50-950 ng / ml, trimester 2 320-1300, trimester 3 130-1700 ng / ml. Results of 300 ng / ml in adult women are normal.
D-dimer examination has a sensitivity of around 93%. Tests with false positive results can occur in other diseases such as liver disorders, rheumatoid arthritis, trauma, pregnancy, inflammation, malignancy / cancer. While false negative results are obtained when patients take blood-thinning drugs or poor examination techniques.
Thus the explanation from me, hopefully useful.