What Causes The Decline In CD4 And CD8?

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Good afternoon. What are the causes of CD4 and CD8 drops besides HIV? Lab results are as follows: HIV rapid check = non-reactive check HBsAg = non-reactive CD 4 = 174CD 8 = 75Anti Toxo IgG = negativeAnti Toxo IgM = negativeAnti Rubella IgG = positive Anti Rubella IgM = negativeAnti CMV IgG = positiveAnti CMV IgM = negativeAnti HSV IgG = negativeAnti HSV IgM = negativeIs the patient at risk of transmitting HIV and TORCH? Thank you

1 Answer:

Good evening Deniiteza, thank you for asking at HealthReplies.com.


CD4 and CD8 are two types of lymphocytes in which both types play an important role in providing immunity against various diseases. Low CD4 and CD8 numbers put the sufferer at risk of infection.


The most common cause of this decrease in lymphocytes is HIV infection, but if it is not caused by HIV, this condition can also be caused by several other diseases such as:

Severe viral / bacterial infections
Autoimmune disease
Patients on immunosuppression therapy (immune-lowering drugs)
Lymphoma
TB infection
Sepsis
Burns
Malnutrition

Due to other causes that can cause a decrease in CD4 and CD8 counts, it is strongly recommended to consult further with a specialist in internal medicine to determine other causes beyond HIV infection due to negative HIV testing results.


Regarding your next question, these results indicate that the patient is not infected with HIV, but has been infected by the CMV and Rubella viruses. Because the patient is not infected with HIV, the patient is not at risk of transmitting HIV to others, but is still at risk of contracting HIV.


For CMV and Rubella infections themselves, because this infection is no longer active (characterized by negative IgM), this patient is also generally not at risk of transmitting TORCH infection to the baby being conceived (to pregnant women) or to others. However, these patients are still at risk of having a TORCH infection.


I hope this helps.

: by

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