Why Are Gout Patients Not Recommended Taking Drugs That Reduce Uric Acid Levels?
I want to ask why do patients with gouty arthritis not recommended taking drugs that reduce blood uric acid levels during acute joint pain attacks?
Hello Elisabeth, thank you for asking HealthReplies.com.
Let me introduce myself, Dr. Rio will try to answer your question.
Treatment for acute gout should be treated as quickly as possible. The use of drugs for initial treatment must pay attention to whether there are contraindications to these drugs or not, and also the history of previous treatment. Based on the literature, the recommended drug for acute gout attacks whose onset is <12 hours is colchicine. Colchicine is one type of drug that has the work of increasing uric acid expenditure through urine.
In addition, NSAIDs, oral corticosteroids can be given and / or joint aspiration is needed followed by corticosteroid injections. Be careful when using these drugs. Colchicine and NSAIDs should not be used carelessly without doctor's advice, due to several contra indications that one of the drugs is in impaired kidney function.
Gout-lowering drugs such as allopurinol are not recommended to start treatment during an acute joint pain attack. However, in patients who are already on routine therapy for gout-lowering drugs, this drug therapy must be continued. Gout-lowering drugs are recommended starting 2 weeks after the acute attack subsides. Indications to start gout-lowering therapy in gout patients are patients with gout attacks ≥2 attacks, patients with gout attacks first with serum uric acid levels ≥ 8 or age <40 years.
That's all the answers I can give. Thank you :)