Why Can’t An MAO Be Given To Patients With Heart Disease?
Why can’t an MAO be given to patients with heart disease?
Good morning, thanks for the question
MAOI is a class of anti-depressant drugs with a mechanism to suppress chemical substances or neurotransmitters in the brain that play a role in the onset of depression. This drug is contraindicated if there is a history of allergy to the drug or component of the drug, patients with a history of heart infarction. MAOI is known to cause hypertensive crises when consumed with certain drugs or foods, such as cheese. This is due to the release of catecholamines from the formation of tyramine in the metabolism of cheese in the body, causing heart muscle injury so that the potential for heart muscle necrosis then occurs heart attack. Therefore this drug administration must also be accompanied by good education about drug interactions and drug side effects.
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